Researchers at the earliest after Sierra Leone declared Ebola cases of genetic research, the virus appeared in more than 300 genetic changes in interpersonal communication process, which may result in the current development of diagnostic tests and the effect of experimental treatments affected.
Ebola outbreak in West Africa
NEW YORK, August 28, researchers reported in the first Ebola case study of Sierra Leone declared the gene, the virus appeared in more than 300 genetic changes in interpersonal communication process, which may result in the current development of diagnostic tests and trials The effect of treatment is affected.
Harvard University’s 萨贝提 is in charge of the study, subjects were sampled Sierra Leone 78 patients, and these patients infection can be traced back to a therapist. This is the name of the patient healing therapists have Ebola patients from Guinea, and the current round of Ebola epidemic which broke out in Guinea initially.
Study published in the journal “Science”, the researchers found that the Ebola virus to mutate rapidly, may affect the current diagnostic techniques and vaccines and therapeutic drugs future.
World Health Organization said the number of people infected with Ebola may more than two million people, the epidemic may spread to more countries. Temporarily unable to contact the World Health Organization on behalf of the latest genetic research on this comment.
Report co-author, Gary Tulane University, said the virus mutation rate in the human body, which is twice the rate of mutation in vivo animal host. These researchers found that the gene sequence promptly published in the Internet, allow other researchers to obtain data as soon as possible.
萨 贝提 this study will harvest due to her laboratory, efforts Tulane University peers and Sierra Leone Ministry of Health over the years in response to Lassa fever regard. Lassa fever and Ebola virus similar. Lassa fever using existing monitoring team, the researchers quickly began sampling for testing.
Some researchers involved in the study sacrificed their lives, including in Sierra Leone was regarded as a “hero doctor” Humar, died after he was infected with the Ebola virus.
The research team using deep sequencing technology, not only to discover how the virus is spread when a variation between people, but also found the virus in the same person’s body is how variation.
However, this study failed to identify whether the virus because the virus mutates to stimulate growth, make it easier to spread, thus accelerating the spread of the epidemic. Gary said it needs further laboratory tests.